Novel Genetic Loci Affecting Facial Shape Variation in Humans

Genetic Mapping of Novel Loci Affecting Canine Blood Phenotypes

Since the publication of the dog genome and the construction of high-quality genome-wide SNP arrays, thousands of dogs have been genotyped for disease studies. For many of these dogs, additional clinical phenotypes are available, such as hematological and clinical chemistry results collected during routine veterinary care. Little is known about the genetic basis of variation in blood phenotypes...

Genetic Factors Affecting Facial Growth

Genetic Variation of Informative Short Tandem Repeat (STR) Loci in an Iranian Population

In the present study, genotyping of six short tandem repeat (STR) loci including CSF1PO, D16S539, F13A01, F13B, LPL and HPRTB was performed on genomic DNA from 127 unrelated individuals from the Iranian province of Isfahan. The results indicated that the allele and genotype distributions were in accordance with Hardy-Weinberg expectations. The observed heterozygosity (Ho), expected heterozygosi...

Sequence variation at two eosinophil-associated ribonuclease loci in humans.

Host defense against invading pathogens is of great importance to the survival of higher organisms. We have been studying the evolution of mammalian eosinophil-associated ribonucleases (EARs), which are members of the ribonuclease A superfamily with known antipathogen activities. Earlier studies showed that positive selection promoted rapid diversification of paralogous EAR genes in both primat...

The mapping of genetic loci affecting streptomycin resistance in Pneumococcus.

HE term “complex locus” implies a series of closely linked genetic deterTminants all of which produce similar or identical modifications in the phenotype of an organism. Much of the experimental work to be described is concerned with a series of this type conferring streptomycin resistance in Pneumococcus. BRYAN (1 961 ) has isolated spontaneous streptomycin-resistant mutants of Pneumococcus wh...